| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-tyrosine-phosphatase |
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| Ligand | BDBM50326497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_658096 (CHEMBL1249161) |
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| IC50 | 50±n/a nM |
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| Citation |  Comeau, AB; Critton, DA; Page, R; Seto, CT A focused library of protein tyrosine phosphatase inhibitors. J Med Chem53:6768-72 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-tyrosine-phosphatase |
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| Name: | Protein-tyrosine-phosphatase |
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| Synonyms: | Secreted effector protein | Secreted protein-tyrosine phosphatase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50881.86 |
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| Organism: | Yersinia pestis |
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| Description: | ChEMBL_810616 |
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| Residue: | 468 |
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| Sequence: | MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVL
SHVANVVLTQEDTAKLLQSTVKHNLNNYDLRSVGNGNSVLVSLRSDQMTLQDAKVLLEAA
LRQESGARGHVSSHSHSALHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARA
TAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAV
RADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPD
YFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAV
SSEVTKALASLVDQTAETKRNMYESKGSSAVGDDSKLRPVIHCRAGVGRTAQLIGAMCMN
DSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
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| BDBM50326497 |
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| n/a |
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| Name | BDBM50326497 |
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| Synonyms: | 4, 4'-[[2-[[(4-(4-Trifluoromethylthio)phenoxyphenyl)amino]carbonyl]-1, 4-phenylene]bis(methyleneoxy)]bis[alpha-oxobenzeneacetic acid] | CHEMBL1240789 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H26F3NO10S |
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| Mol. Mass. | 745.674 |
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| SMILES | OC(=O)C(=O)c1ccc(OCc2ccc(COc3ccc(cc3)C(=O)C(O)=O)c(c2)C(=O)Nc2ccc(Oc3ccc(SC(F)(F)F)cc3)cc2)cc1 |
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| Structure | 
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