| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50151891 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_662800 (CHEMBL1252539) |
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| Ki | 7.7±n/a nM |
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| Citation |  Huang, H; Player, MR Bradykinin B1 receptor antagonists as potential therapeutic agents for pain. J Med Chem53:5383-99 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1R | BDKRB1 | BK-1 receptor | BKRB1_MACMU |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40259.67 |
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| Organism: | Macaca mulatta |
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| Description: | ChEMBL_662800 |
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| Residue: | 352 |
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| Sequence: | MASWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLV
FLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANL
FISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAV
PDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCG
GSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLA
FTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50151891 |
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| n/a |
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| Name | BDBM50151891 |
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| Synonyms: | CHEMBL273869 | {2-(2,2-Diphenyl-ethylamino)-5-[4-(4-methyl-piperazine-1-carbonyl)-piperidine-1-sulfonyl]-phenyl}-morpholin-4-yl-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C36H45N5O5S |
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| Mol. Mass. | 659.838 |
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| SMILES | CN1CCN(CC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(NCC(c2ccccc2)c2ccccc2)c(c1)C(=O)N1CCOCC1 |
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| Structure | 
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