| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
|---|
| Ligand | BDBM50326716 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_661558 (CHEMBL1253122) |
|---|
| Ki | >1000±n/a nM |
|---|
| Citation |  Borthwick, AD Oral oxytocin antagonists. J Med Chem53:6525-38 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V2 receptor |
|---|
| Name: | Vasopressin V2 receptor |
|---|
| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
|---|
| Type: | G-protein coupled receptor |
|---|
| Mol. Mass.: | 40761.85 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 371 |
|---|
| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
|
|
|
|---|
| BDBM50326716 |
|---|
| n/a |
|---|
| Name | BDBM50326716 |
|---|
| Synonyms: | (R)-4-chloro-3-(5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxoindolin-3-yl)-N-ethyl-N-(pyridin-3-ylmethyl)benzamide hydrochloride | CHEMBL1253499 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H31Cl2N3O4 |
|---|
| Mol. Mass. | 604.523 |
|---|
| SMILES | CCN(Cc1cccnc1)C(=O)c1ccc(Cl)c(c1)[C@]1(C)C(=O)N(Cc2ccc(OC)cc2OC)c2ccc(Cl)cc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
