| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1b receptor |
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| Ligand | BDBM50326716 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_661572 (CHEMBL1253136) |
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| Ki | 46±n/a nM |
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| Citation |  Borthwick, AD Oral oxytocin antagonists. J Med Chem53:6525-38 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1b receptor |
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| Name: | Vasopressin V1b receptor |
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| Synonyms: | Avpr1b | V1BR_RAT | VASOPRESSIN V1B | Vasopressin V1b receptor | Vasopressin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47104.48 |
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| Organism: | RAT |
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| Description: | VASOPRESSIN V1B AVPR1B RAT::P48974 |
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| Residue: | 425 |
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| Sequence: | MNSEPSWTATPSPGGTLPVPNATTPWLGRDEELAKVEIGILATVLVLATGGNLAVLLTLG
RHGHKRSRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQGSDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLRQPSQSTYPLIAAPWLLAAILSLPQVFIFSLREVIQG
SGVLDCWADFYFSWGPRAYITWTTMAIFVLPVAVLSACYGLICHEIYKNLKVKTQAGREE
RRGWRTWDKSSSSAVATAATRGLPSRVSSISTISRAKIRTVKMTFVIVLAYIACWAPFFS
VQMWSVWDENAPNEDSTNVAFTISMLLGNLSSCCNPWIYMGFNSRLLPRSLSHHACCTGS
KPQVHRQLSTSSLTSRRTTLLTHACGSPTLRLSLNLSLRAKPRPAGSLKDLEQVDGEATM
ETSIF
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| BDBM50326716 |
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| n/a |
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| Name | BDBM50326716 |
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| Synonyms: | (R)-4-chloro-3-(5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxoindolin-3-yl)-N-ethyl-N-(pyridin-3-ylmethyl)benzamide hydrochloride | CHEMBL1253499 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H31Cl2N3O4 |
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| Mol. Mass. | 604.523 |
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| SMILES | CCN(Cc1cccnc1)C(=O)c1ccc(Cl)c(c1)[C@]1(C)C(=O)N(Cc2ccc(OC)cc2OC)c2ccc(Cl)cc12 |r| |
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| Structure | 
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