| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50328452 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_665577 (CHEMBL1261461) |
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| Ki | 290±n/a nM |
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| Citation |  Skultety, M; Hübner, H; Löber, S; Gmeiner, P Bioisosteric replacement leading to biologically active [2.2]paracyclophanes with altered binding profiles for aminergic G-protein-coupled receptors. J Med Chem53:7219-28 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50328452 |
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| n/a |
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| Name | BDBM50328452 |
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| Synonyms: | 4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-(2,5-dimethylphenyl)-butan-1-one | CHEMBL1258155 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28ClNO |
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| Mol. Mass. | 369.928 |
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| SMILES | Cc1ccc(C)c(c1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 |
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| Structure | 
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