| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50328483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_665656 (CHEMBL1261587) |
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| Ki | 0.086±n/a nM |
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| Citation |  Kristensen, JL; Püschl, A; Jensen, M; Risgaard, R; Christoffersen, CT; Bang-Andersen, B; Balle, T Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity fora(1)-adrenoceptors. J Med Chem53:7021-34 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51492.08 |
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| Organism: | CALF |
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| Description: | adrenergic Alpha1 0 CALF |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
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| BDBM50328483 |
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| n/a |
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| Name | BDBM50328483 |
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| Synonyms: | 1-Methyl-4-(8-(1-methyl-1H-1,2,4-triazol-3-yl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine | CHEMBL1258988 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25N5S |
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| Mol. Mass. | 391.532 |
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| SMILES | CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(cc12)-c1ncn(C)n1 |
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| Structure | 
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