| Reaction Details |
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 | Report a problem with these data |
| Target | Protein arginine N-methyltransferase 6 |
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| Ligand | BDBM50328743 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675523 (CHEMBL1273736) |
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| IC50 | 39200±n/a nM |
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| Citation |  Feng, Y; Li, M; Wang, B; Zheng, YG Discovery and mechanistic study of a class of protein arginine methylation inhibitors. J Med Chem53:6028-39 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein arginine N-methyltransferase 6 |
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| Name: | Protein arginine N-methyltransferase 6 |
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| Synonyms: | ANM6_HUMAN | HRMT1L6 | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 | Histone-arginine N-methyltransferase PRMT6 | PRMT6 | Protein arginine methyltransferase 6 (PRMT6) |
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| Type: | Protein |
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| Mol. Mass.: | 41928.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 375 |
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| Sequence: | MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM
IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA
REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE
GGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG
LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE
SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK
VGDQEEKTKDFAMED
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| BDBM50328743 |
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| n/a |
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| Name | BDBM50328743 |
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| Synonyms: | 3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-hydroxy-6-((E)-phenyldiazenyl)-7-sulfonaphthalen-2-yl)ureido)naphthalene-2-sulfonate | 3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-hydroxy-6-(phenyldiazenyl)-7-sulfonaphthalen-2-yl)ureido)naphthalene-2-sulfonic acid | CHEMBL1092740 | NSC-47762 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H27N7O10S2 |
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| Mol. Mass. | 769.76 |
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| SMILES | CC(=O)Nc1ccc(cc1)N=Nc1c(O)c2ccc(NC(=O)Nc3ccc4c(O)c(N=Nc5ccccc5)c(cc4c3)S(O)(=O)=O)cc2cc1S(O)(=O)=O |w:31.32,11.12| |
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| Structure | 
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