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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 4 | ||
| Ligand | BDBM50328800 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_673775 (CHEMBL1274952) | ||
| Ki | 19±n/a nM | ||
| Citation |  O'Connor, SP; Wang, Y; Simpkins, LM; Brigance, RP; Meng, W; Wang, A; Kirby, MS; Weigelt, CA; Hamann, LG Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors. Bioorg Med Chem Lett20:6273-6 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 4 | |||
| Name: | Dipeptidyl peptidase 4 | ||
| Synonyms: | ADABP | ADCP2 | Adenosine deaminase complexing protein 2 | CD26 | CD_antigen=CD26 | DPP IV | DPP4 | DPP4_HUMAN | DPPIV | Dipeptidyl peptidase 4 (DDP-IV) | Dipeptidyl peptidase 4 (DPP IV) | Dipeptidyl peptidase 4 (DPP-4) | Dipeptidyl peptidase 4 (DPP4) | Dipeptidyl peptidase 4 (DPPIV) | Dipeptidyl peptidase 4 membrane form | Dipeptidyl peptidase 4 soluble form | Dipeptidyl peptidase IV | Dipeptidyl peptidase IV (DDP-4) | Dipeptidyl peptidase IV (DDP-IV) | Dipeptidyl peptidase IV (DPP IV) | Dipeptidyl peptidase IV membrane form | Dipeptidyl peptidase IV soluble form | Dipeptidyl peptidase-IV (DPP-4) | Dipeptidyl peptidase-IV (DPP-IV) | T-cell activation antigen CD26 | TP103 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 88271.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P27487 | ||
| Residue: | 766 | ||
| Sequence: |
| ||
| BDBM50328800 | |||
| n/a | |||
| Name | BDBM50328800 | ||
| Synonyms: | (2-(2-methoxyphenyl)-7-methyl-5-(2,4,6-trichlorophenyl)imidazo[1,2-a]pyrimidin-6-yl)methanamine | CHEMBL1271270 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H17Cl3N4O | ||
| Mol. Mass. | 447.745 | ||
| SMILES | COc1ccccc1-c1cn2c(c(CN)c(C)nc2n1)-c1c(Cl)cc(Cl)cc1Cl |(24.28,-40,;25.05,-41.33,;24.28,-42.66,;22.74,-42.66,;21.96,-44,;22.74,-45.33,;24.28,-45.33,;25.04,-44,;26.58,-44,;27.48,-45.25,;28.94,-44.77,;30.28,-45.54,;31.62,-44.77,;32.95,-45.54,;34.28,-44.77,;31.61,-43.22,;32.94,-42.45,;30.28,-42.46,;28.95,-43.23,;27.48,-42.76,;30.28,-47.08,;28.94,-47.85,;27.61,-47.08,;28.94,-49.39,;30.28,-50.16,;30.28,-51.7,;31.62,-49.38,;31.61,-47.84,;32.94,-47.07,)| | ||
| Structure | 
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