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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 9 | ||
| Ligand | BDBM50328791 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_673773 (CHEMBL1274950) | ||
| Ki | >30000±n/a nM | ||
| Citation |  O'Connor, SP; Wang, Y; Simpkins, LM; Brigance, RP; Meng, W; Wang, A; Kirby, MS; Weigelt, CA; Hamann, LG Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors. Bioorg Med Chem Lett20:6273-6 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 9 | |||
| Name: | Dipeptidyl peptidase 9 | ||
| Synonyms: | DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 98260.70 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q86TI2 | ||
| Residue: | 863 | ||
| Sequence: |
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| BDBM50328791 | |||
| n/a | |||
| Name | BDBM50328791 | ||
| Synonyms: | (5-(2,6-dichlorophenyl)-2-(2-methoxyphenyl)-7-methylimidazo[1,2-a]pyrimidin-6-yl)methanamine | CHEMBL1270758 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H18Cl2N4O | ||
| Mol. Mass. | 413.3 | ||
| SMILES | COc1ccccc1-c1cn2c(c(CN)c(C)nc2n1)-c1c(Cl)cccc1Cl |(26.4,-3.77,;27.16,-5.11,;26.39,-6.44,;24.85,-6.43,;24.08,-7.77,;24.86,-9.11,;26.39,-9.1,;27.16,-7.78,;28.69,-7.77,;29.6,-9.02,;31.06,-8.55,;32.39,-9.32,;33.73,-8.55,;35.07,-9.31,;36.4,-8.54,;33.73,-6.99,;35.06,-6.22,;32.39,-6.23,;31.06,-7.01,;29.6,-6.53,;32.4,-10.85,;33.73,-11.62,;35.06,-10.85,;33.73,-13.16,;32.39,-13.93,;31.06,-13.16,;31.06,-11.62,;29.73,-10.85,)| | ||
| Structure | 
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