| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50329760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_674745 (CHEMBL1273998) |
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| Kd | 1700±n/a nM |
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| Citation |  Sudžius, J; Baranauskiene, L; Golovenko, D; Matuliene, J; Michailoviene, V; Torresan, J; Jachno, J; Sukackaite, R; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. Bioorg Med Chem18:7413-21 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50329760 |
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| n/a |
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| Name | BDBM50329760 |
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| Synonyms: | 4-[N-(6-Chloro-5-cyano-2-methylthiopyrimidin-4-yl)amino]benzenesulfonamide | CHEMBL1272233 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10ClN5O2S2 |
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| Mol. Mass. | 355.823 |
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| SMILES | CSc1nc(Cl)c(C#N)c(Nc2ccc(cc2)S(N)(=O)=O)n1 |
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| Structure | 
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