| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM10880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_674747 (CHEMBL1274000) |
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| Kd | 65±n/a nM |
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| Citation |  Sudžius, J; Baranauskiene, L; Golovenko, D; Matuliene, J; Michailoviene, V; Torresan, J; Jachno, J; Sukackaite, R; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. Bioorg Med Chem18:7413-21 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29445.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8N1Q1 |
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| Residue: | 262 |
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| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
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| BDBM10880 |
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| n/a |
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| Name | BDBM10880 |
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| Synonyms: | AZA | AZA2 | AZM acetazolamide | Acerazolamide, AAZ | Acetazolamide | Acetazolamide (AAZ) | Acetazolamide (AZA) | Acetazolamide (AZM) | Acetazolamide, 5 | Acetazolamide, AAZ | Acetazolamide, AZA | Acetazolamide, AZM | CHEMBL20 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Sulfonamide, 1 | US10172837, Acetazolamide | US11278534, Example acetazolamide | US11535599, Example acetazolamide | sulfonamide 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H6N4O3S2 |
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| Mol. Mass. | 222.245 |
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| SMILES | CC(=O)Nc1nnc(s1)S(N)(=O)=O |
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| Structure | 
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