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TargetCytochrome P450 1A1
LigandBDBM50330386
Substrate/Competitorn/a
Meas. Tech.ChEMBL_684297
Kd 2250±n/a nM
Citation Rosales-Hernández MCMendieta-Wejebe JETrujillo-Ferrara JGCorrea-Basurto J Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays. Eur J Med Chem 45:4845-55 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cytochrome P450 1A1
Name:Cytochrome P450 1A
Synonyms:CYPIA1 | Cytochrome P450 1A | Cytochrome P450 1A1 (CYP1A1) | P450 form 6 | P450-C | P450-P1
Type:Protein
Mol. Mass.:58177.23
Organism:Homo sapiens (Human)
Description:P04798
Residue:512
Sequence:
MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH
LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS
MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG
PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL
RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV
QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS
DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL
WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF
SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
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  Blast E-value cutoff:
BDBM50330386
n/a
NameBDBM50330386
Synonyms:4-(4'-hydroxy-phenylamino)-4-oxo propanoic acid | CHEMBL1275862
TypeSmall organic molecule
Emp. Form.C10H11NO4
Mol. Mass.209.1986
SMILESOC(=O)CCC(=O)Nc1ccc(O)cc1
Structure
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