| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyribonuclease gamma |
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| Ligand | BDBM50333186 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_698121 (CHEMBL1646041) |
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| IC50 | 34500±n/a nM |
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| Citation |  Yamada, Y; Fujii, T; Ishijima, R; Tachibana, H; Yokoue, N; Takasawa, R; Tanuma, S DR396, an apoptotic DNase¿ inhibitor, attenuates high mobility group box 1 release from apoptotic cells. Bioorg Med Chem19:168-71 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyribonuclease gamma |
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| Name: | Deoxyribonuclease gamma |
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| Synonyms: | DHP2 | DNAS1L3 | DNASE1L3 | DNSL3_HUMAN | DNase I homolog protein DHP2 | DNase I-like 3 | DNase gamma | Deoxyribonuclease I-like 3 | LS-DNase | LSD | Liver and spleen DNase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35519.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1457551 |
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| Residue: | 305 |
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| Sequence: | MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
KSKRS
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| BDBM50333186 |
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| n/a |
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| Name | BDBM50333186 |
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| Synonyms: | (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-cyclohexylpropanoic acid | CHEMBL1644887 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27NO4 |
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| Mol. Mass. | 393.4755 |
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| SMILES | OC(=O)[C@@H](CC1CCCCC1)NC(=O)OCC1c2ccccc2-c2ccccc12 |r| |
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| Structure | 
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