| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
|---|
| Ligand | BDBM4703 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_700657 (CHEMBL1645696) |
|---|
| Ki | 887±n/a nM |
|---|
| Citation |  Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett21:710-4 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 6 |
|---|
| Name: | Carbonic anhydrase 6 |
|---|
| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35371.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P23280 |
|---|
| Residue: | 308 |
|---|
| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
|
|
|
|---|
| BDBM4703 |
|---|
| n/a |
|---|
| Name | BDBM4703 |
|---|
| Synonyms: | 4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic acid | Benzoic Acid deriv. 31 | CHEMBL414 | JMC522226 Compound 22 | JMC523116 Compound 22 | JMC52646 Compound 23 | aromatic/heteroaromatic sulfonamide 23 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H7NO4S |
|---|
| Mol. Mass. | 201.2 |
|---|
| SMILES | NS(=O)(=O)c1ccc(cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
