| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase N2 |
|---|
| Ligand | BDBM50335374 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_701646 (CHEMBL1656538) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Liniger, M; Neuhaus, C; Hofmann, T; Fransioli-Ignazio, L; Jordi, M; Drueckes, P; Trappe, Js; Fabbro, D Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277 ACS Med Chem Lett2:22-27 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase N2 |
|---|
| Name: | Serine/threonine-protein kinase N2 |
|---|
| Synonyms: | PKN2 | PKN2_HUMAN | PRK2 | PRKCL2 | Protein kinase C-like 2 | Protein kinase N2 | Protein-kinase C-related kinase 2 | Serine/threonine-protein kinase N2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 112029.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1433151 |
|---|
| Residue: | 984 |
|---|
| Sequence: | MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL
KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR
TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL
QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM
KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA
ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS
PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK
FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN
PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV
PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG
QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC
AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL
VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY
RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW
WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL
GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP
REPRILSEEEQEMFRDFDYIADWC
|
|
|
|---|
| BDBM50335374 |
|---|
| n/a |
|---|
| Name | BDBM50335374 |
|---|
| Synonyms: | (3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione | CHEMBL1651521 | CHEMBL1651522 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24O6 |
|---|
| Mol. Mass. | 348.3903 |
|---|
| SMILES | COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17| |
|---|
| Structure | 
|
|---|
Search and Browse
