| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lutropin-choriogonadotropic hormone receptor |
|---|
| Ligand | BDBM50335467 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_702109 (CHEMBL1655339) |
|---|
| EC50 | 1±n/a nM |
|---|
| Citation |  Bonger, KM; Hoogendoorn, S; van Koppen, CJ; Timmers, CM; Marel, GA Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist ACS Med Chem Lett2:85-89 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lutropin-choriogonadotropic hormone receptor |
|---|
| Name: | Lutropin-choriogonadotropic hormone receptor |
|---|
| Synonyms: | LCGR | LGR2 | LH/CG-R | LHCGR | LHR | LHRHR | LSH-R | LSHR_HUMAN | Luteinizing hormone receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 78662.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_562598 |
|---|
| Residue: | 699 |
|---|
| Sequence: | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
|
|
|
|---|
| BDBM50335467 |
|---|
| n/a |
|---|
| Name | BDBM50335467 |
|---|
| Synonyms: | 5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-(prop-2-ynylamino)ethylamino)phenyl)thieno[2,3-d]pyrimidine-6-carboxamide | CHEMBL1651721 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26N6O2S2 |
|---|
| Mol. Mass. | 482.622 |
|---|
| SMILES | CSc1nc(-c2cccc(NCC(=O)NCC#C)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
