| Reaction Details |
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 | Report a problem with these data |
| Target | Lutropin-choriogonadotropic hormone receptor |
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| Ligand | BDBM50335476 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_702109 (CHEMBL1655339) |
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| EC50 | 75±n/a nM |
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| Citation |  Bonger, KM; Hoogendoorn, S; van Koppen, CJ; Timmers, CM; Marel, GA Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist ACS Med Chem Lett2:85-89 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lutropin-choriogonadotropic hormone receptor |
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| Name: | Lutropin-choriogonadotropic hormone receptor |
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| Synonyms: | LCGR | LGR2 | LH/CG-R | LHCGR | LHR | LHRHR | LSH-R | LSHR_HUMAN | Luteinizing hormone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78662.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_562598 |
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| Residue: | 699 |
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| Sequence: | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
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| BDBM50335476 |
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| n/a |
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| Name | BDBM50335476 |
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| Synonyms: | (S)-4-(3-(2-((1-(2-(2-(2-(4-((4-(1-acetyl-6-biphenyl-4-ylcarboxamido-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-4-yl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methylamino)-2-oxoethylamino)phenyl)-5-amino-N-tert-butyl-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide | CHEMBL1651821 |
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| Type | Small organic molecule |
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| Emp. Form. | C65H72N14O7S2 |
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| Mol. Mass. | 1225.487 |
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| SMILES | CSc1nc(-c2cccc(NCC(=O)NCc3cn(CCOCCOCCn4cc(COc5ccc(cc5)[C@]5(C)CC(C)(C)N(C(C)=O)c6ccc(NC(=O)c7ccc(cc7)-c7ccccc7)cc56)nn4)nn3)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C |r| |
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| Structure | 
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