| Reaction Details |
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 | Report a problem with these data |
| Target | Telomere resolvase ResT |
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| Ligand | BDBM50335558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_713937 (CHEMBL1660353) |
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| IC50 | 3160±n/a nM |
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| Citation |  Lefas, G; Chaconas, G High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete. Antimicrob Agents Chemother53:4441-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Telomere resolvase ResT |
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| Name: | Telomere resolvase ResT |
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| Synonyms: | REST_BORBU | resT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.70 |
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| Organism: | Borrelia burgdorferi |
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| Description: | ChEMBL_713937 |
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| Residue: | 449 |
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| Sequence: | MPPKVKIKNDFEIFRKELEILYKKYLNNELSYLKLKEKLKILAENHKAILFRKDKFTNRS
IILNLSKTRKIIKEYINLSVIERIRRDNTFLFFWKSRRIKELKNIGIKDRKKIEELIFSN
QMNDEKSYFQYFIDLFVTPKWLNDYAHKYKIEKINSYRKEQIFVKINLNTYIEIIKLLLN
QSRDIRLKFYGVLMAIGRRPVEVMKLSQFYIADKNHIRMEFIAKKRENNIVNEVVFPVFA
DPELIINSIKEIRYMEQTENLTKEIISSNLAYSYNRLFRQIFNNIFAPEESVYFCRAIYC
KFSYLAFAPKNMEMNYWITKVLGHEPNDITTAFHYNRYVLDNLDDKADNSLLTLLNQRIY
TYVRRKATYSTLTMDRLESLIKEHHIFDDNYIKTLIVIKNLMLKDNLETLAMVRGLNVKI
RKAFKATYGYNYNYIKLTEYLSIIFNYKL
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| BDBM50335558 |
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| n/a |
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| Name | BDBM50335558 |
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| Synonyms: | 2-(4-(6-(6-carboxy-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-1H-benzo[d]imidazol-2-yl)phenyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-6-carboxylic acid | CHEMBL1649740 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H20N4O8 |
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| Mol. Mass. | 672.5981 |
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| SMILES | OC(=O)c1ccc2C(=O)N(C(=O)c3cccc1c23)c1ccc(cc1)-c1nc2ccc(cc2[nH]1)N1C(=O)c2cccc3c(ccc(C1=O)c23)C(O)=O |
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| Structure | 
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