| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Telomere resolvase ResT |
|---|
| Ligand | BDBM50335560 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_713937 (CHEMBL1660353) |
|---|
| IC50 | 2730±n/a nM |
|---|
| Citation |  Lefas, G; Chaconas, G High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete. Antimicrob Agents Chemother53:4441-9 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Telomere resolvase ResT |
|---|
| Name: | Telomere resolvase ResT |
|---|
| Synonyms: | REST_BORBU | resT |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54325.70 |
|---|
| Organism: | Borrelia burgdorferi |
|---|
| Description: | ChEMBL_713937 |
|---|
| Residue: | 449 |
|---|
| Sequence: | MPPKVKIKNDFEIFRKELEILYKKYLNNELSYLKLKEKLKILAENHKAILFRKDKFTNRS
IILNLSKTRKIIKEYINLSVIERIRRDNTFLFFWKSRRIKELKNIGIKDRKKIEELIFSN
QMNDEKSYFQYFIDLFVTPKWLNDYAHKYKIEKINSYRKEQIFVKINLNTYIEIIKLLLN
QSRDIRLKFYGVLMAIGRRPVEVMKLSQFYIADKNHIRMEFIAKKRENNIVNEVVFPVFA
DPELIINSIKEIRYMEQTENLTKEIISSNLAYSYNRLFRQIFNNIFAPEESVYFCRAIYC
KFSYLAFAPKNMEMNYWITKVLGHEPNDITTAFHYNRYVLDNLDDKADNSLLTLLNQRIY
TYVRRKATYSTLTMDRLESLIKEHHIFDDNYIKTLIVIKNLMLKDNLETLAMVRGLNVKI
RKAFKATYGYNYNYIKLTEYLSIIFNYKL
|
|
|
|---|
| BDBM50335560 |
|---|
| n/a |
|---|
| Name | BDBM50335560 |
|---|
| Synonyms: | 2,2'-(3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulene-1,8-diyl)bis(5,7-dihydroxychroman-3,2-diyl)bis(3,4,5-trihydroxybenzoate) | CHEMBL1451483 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C43H32O20 |
|---|
| Mol. Mass. | 868.7022 |
|---|
| SMILES | Oc1cc(O)c2CC(OC(=O)c3cc(O)c(O)c(O)c3)C(Oc2c1)c1cc(O)c(O)c2c1cc(cc(O)c2=O)C1Oc2cc(O)cc(O)c2CC1OC(=O)c1cc(O)c(O)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
