| Reaction Details |
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 | Report a problem with these data |
| Target | Telomere resolvase ResT |
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| Ligand | BDBM50335561 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_713937 (CHEMBL1660353) |
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| IC50 | 1960±n/a nM |
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| Citation |  Lefas, G; Chaconas, G High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete. Antimicrob Agents Chemother53:4441-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Telomere resolvase ResT |
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| Name: | Telomere resolvase ResT |
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| Synonyms: | REST_BORBU | resT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.70 |
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| Organism: | Borrelia burgdorferi |
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| Description: | ChEMBL_713937 |
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| Residue: | 449 |
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| Sequence: | MPPKVKIKNDFEIFRKELEILYKKYLNNELSYLKLKEKLKILAENHKAILFRKDKFTNRS
IILNLSKTRKIIKEYINLSVIERIRRDNTFLFFWKSRRIKELKNIGIKDRKKIEELIFSN
QMNDEKSYFQYFIDLFVTPKWLNDYAHKYKIEKINSYRKEQIFVKINLNTYIEIIKLLLN
QSRDIRLKFYGVLMAIGRRPVEVMKLSQFYIADKNHIRMEFIAKKRENNIVNEVVFPVFA
DPELIINSIKEIRYMEQTENLTKEIISSNLAYSYNRLFRQIFNNIFAPEESVYFCRAIYC
KFSYLAFAPKNMEMNYWITKVLGHEPNDITTAFHYNRYVLDNLDDKADNSLLTLLNQRIY
TYVRRKATYSTLTMDRLESLIKEHHIFDDNYIKTLIVIKNLMLKDNLETLAMVRGLNVKI
RKAFKATYGYNYNYIKLTEYLSIIFNYKL
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| BDBM50335561 |
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| n/a |
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| Name | BDBM50335561 |
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| Synonyms: | (R)-4-((5S,8R,9S,10S,13S,14S,17R)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | CHEMBL1649742 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H40O2 |
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| Mol. Mass. | 360.5732 |
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| SMILES | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CCCC[C@]4(C)[C@H]3CC[C@@]12C |r| |
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| Structure | 
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