| Reaction Details |
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 | Report a problem with these data |
| Target | Aminopeptidase N |
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| Ligand | BDBM50336496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_716908 (CHEMBL1670936) |
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| IC50 | 310000±n/a nM |
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| Citation |  Albrecht, S; Al-Lakkis-Wehbe, M; Orsini, A; Defoin, A; Pale, P; Salomon, E; Tarnus, C; Weibel, JM Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13. Bioorg Med Chem19:1434-49 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminopeptidase N |
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| Name: | Aminopeptidase N |
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| Synonyms: | AMPN_HUMAN | ANPEP | APN | Alanyl aminopeptidase | Aminopeptidase | CD13 | CD_antigen=CD13 | Microsomal aminopeptidase | Myeloid plasma membrane glycoprotein CD13 | PEPN | gp150 | hAPN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 109522.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507526 |
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| Residue: | 967 |
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| Sequence: | MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPA
SATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVI
IIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDS
EFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP
KDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLI
RIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLV
TYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL
GADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKG
ASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIM
NRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDY
WLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQ
IINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKN
YLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWM
ENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWI
LNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSN
LIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQ
WFTENSK
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| BDBM50336496 |
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| n/a |
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| Name | BDBM50336496 |
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| Synonyms: | 2-aminocycloheptanone hydrochloride | CHEMBL1668627 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H13NO |
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| Mol. Mass. | 127.1842 |
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| SMILES | NC1CCCCCC1=O |
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| Structure | 
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