| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 130 |
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| Ligand | BDBM31774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_721240 (CHEMBL1675117) |
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| Kd | 13300±n/a nM |
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| Citation |  Warrilow, AG; Jackson, CJ; Parker, JE; Marczylo, TH; Kelly, DE; Lamb, DC; Kelly, SL Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae. Antimicrob Agents Chemother53:1157-64 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 130 |
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| Name: | Cytochrome P450 130 |
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| Synonyms: | CP130_MYCTU | Cytochrome P450 130 (G243A) | Putative cytochrome P450 130 | cyp130 |
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| Type: | Enzyme |
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| Mol. Mass.: | 44574.98 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WPN5 |
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| Residue: | 405 |
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| Sequence: | MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR
DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV
RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD
GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD
VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA
RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
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| BDBM31774 |
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| n/a |
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| Name | BDBM31774 |
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| Synonyms: | CHEMBL104 | Canesten | Clotrimazole | Lotrimin | Mycelex | US9138393, Clotrimazole | cid_2812 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17ClN2 |
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| Mol. Mass. | 344.837 |
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| SMILES | Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 |
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| Structure | 
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