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TargetCarbonic Anhydrase 2 (Can2)
LigandBDBM50339592
Substrate/Competitorn/a
Meas. Tech.ChEMBL_736725
Ki 890±n/a nM
Citation Davis RAHofmann AOsman AHall RAMühlschlegel FAVullo DInnocenti ASupuran CTPoulsen SA Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. J Med Chem 54:1682-92 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic Anhydrase 2 (Can2)
Name:Carbonic Anhydrase 2 (Can2)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:26594.37
Organism:Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii)
Description:n/a
Residue:239
Sequence:
MPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQA
PNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVM
VVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMA
VKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPFVDDRVPRA
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  Blast E-value cutoff:
BDBM50339592
n/a
NameBDBM50339592
Synonyms:2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imidazol-5(4H)-one | CHEMBL603189
TypeSmall organic molecule
Emp. Form.C11H11N3O3
Mol. Mass.233.2233
SMILESCOc1cc(C=C2N=C(N)NC2=O)ccc1O |w:5.4,t:7|
Structure
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