| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50340653 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_739585 (CHEMBL1763411) |
|---|
| IC50 | 9670±n/a nM |
|---|
| Citation |  Delogu, G; Picciau, C; Ferino, G; Quezada, E; Podda, G; Uriarte, E; Viña, D Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives. Eur J Med Chem46:1147-52 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59689.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21397 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
|
|
|
|---|
| BDBM50340653 |
|---|
| n/a |
|---|
| Name | BDBM50340653 |
|---|
| Synonyms: | 3-(Indol-3-yl)-7-methoxycoumarin | CHEMBL1761762 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H13NO3 |
|---|
| Mol. Mass. | 291.3007 |
|---|
| SMILES | COc1ccc2cc(-c3c[nH]c4ccccc34)c(=O)oc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
