| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Membrane primary amine oxidase |
|---|
| Ligand | BDBM50341610 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_742890 (CHEMBL1769940) |
|---|
| IC50 | 150±n/a nM |
|---|
| Citation |  Nurminen, EM; Pihlavisto, M; Lázár, L; Pentikäinen, U; Fülöp, F; Pentikäinen, OT Novel hydrazine molecules as tools to understand the flexibility of vascular adhesion protein-1 ligand-binding site: toward more selective inhibitors. J Med Chem54:2143-54 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Membrane primary amine oxidase |
|---|
| Name: | Membrane primary amine oxidase |
|---|
| Synonyms: | AOC3 | AOC3_HUMAN | Amine oxidase, copper containing | Semicarbazide-sensitive amine oxidase (SSAO) | Semicarbazide-sensitive amine oxidase/ Vascular adhesion protein 1 (SSAO/VAP-1) | VAP1 | Vascular adhesion protein 1 (VAP-1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 84620.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q16853 |
|---|
| Residue: | 763 |
|---|
| Sequence: | MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF
ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP
AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID
QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL
HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW
SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV
YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ
APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH
PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW
AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP
RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF
SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA
DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN
|
|
|
|---|
| BDBM50341610 |
|---|
| n/a |
|---|
| Name | BDBM50341610 |
|---|
| Synonyms: | (S)-2-Hydrazino-1-phenylethanol | CHEMBL1766381 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H12N2O |
|---|
| Mol. Mass. | 152.1937 |
|---|
| SMILES | NNC[C@@H](O)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
