| Reaction Details |
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 | Report a problem with these data |
| Target | 6-phosphogluconate dehydrogenase, decarboxylating |
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| Ligand | BDBM50148767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_744988 (CHEMBL1772003) |
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| Ki | 10±n/a nM |
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| Citation |  Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett21:2679-82 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 6-phosphogluconate dehydrogenase, decarboxylating |
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| Name: | 6-phosphogluconate dehydrogenase, decarboxylating |
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| Synonyms: | 6-phosphogluconate dehydrogenase, decarboxylating, putative |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52169.87 |
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| Organism: | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) |
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| Description: | ChEMBL_744988 |
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| Residue: | 479 |
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| Sequence: | MSMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM
EAFAASLKKPRKALILVQAGAATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA
AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG
AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA
AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ
ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL
NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS
KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ
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| BDBM50148767 |
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| n/a |
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| Name | BDBM50148767 |
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| Synonyms: | 2,3-dihydroxy-4-(hydroxyamino)-4-oxobutyl dihydrogen phosphate | 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID | CHEMBL116018 | Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydroxycarbamoyl-propyl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C4H10NO8P |
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| Mol. Mass. | 231.0979 |
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| SMILES | ONC(=O)[C@H](O)[C@H](O)COP(O)(O)=O |
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| Structure | 
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