| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50158776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_744131 (CHEMBL1771830) |
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| Ki | 9±n/a nM |
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| Citation |  Cheong, SL; Federico, S; Venkatesan, G; Paira, P; Shao, YM; Spalluto, G; Yap, CW; Pastorin, G Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorg Med Chem Lett21:2898-905 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50158776 |
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| n/a |
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| Name | BDBM50158776 |
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| Synonyms: | 1-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-isopropyl-urea | CHEMBL361412 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N8O2 |
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| Mol. Mass. | 430.4625 |
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| SMILES | CC(C)NC(=O)Nc1nc2nn(CCc3ccccc3)cc2c2nc(nn12)-c1ccco1 |
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| Structure | 
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