| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
|---|
| Ligand | BDBM50343602 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_746050 (CHEMBL1775437) |
|---|
| Ki | 0.012±n/a nM |
|---|
| Citation |  Koike, T; Hoashi, Y; Takai, T; Nakayama, M; Yukuhiro, N; Ishikawa, T; Hirai, K; Uchikawa, O 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT2-selective agonists. J Med Chem54:3436-44 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1B |
|---|
| Name: | Melatonin receptor type 1B |
|---|
| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40203.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49286 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
|---|
| BDBM50343602 |
|---|
| n/a |
|---|
| Name | BDBM50343602 |
|---|
| Synonyms: | CHEMBL1774519 | N-{2-[7-(Cyclohexylmethyl)-1,6-dihydro-2H-indeno[5,4-b]-furan-8-yl]ethyl}acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H29NO2 |
|---|
| Mol. Mass. | 339.4712 |
|---|
| SMILES | CC(=O)NCCC1=C(CC2CCCCC2)Cc2ccc3OCCc3c12 |c:6| |
|---|
| Structure | 
|
|---|
Search and Browse
