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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sigma non-opioid intracellular receptor 1 | ||
| Ligand | BDBM50344427 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_748646 (CHEMBL1780499) | ||
| Ki | >1000±n/a nM | ||
| Citation |  Rack, E; Fröhlich, R; Schepmann, D; Wünsch, B Design, synthesis and pharmacological evaluation of spirocyclics(1) receptor ligands with exocyclic amino moiety (increased distance 1). Bioorg Med Chem19:3141-51 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sigma non-opioid intracellular receptor 1 | |||
| Name: | Sigma non-opioid intracellular receptor 1 | ||
| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein | ||
| Type: | Protein | ||
| Mol. Mass.: | 25307.17 | ||
| Organism: | Cavia porcellus (Guinea pig) | ||
| Description: | Q60492 | ||
| Residue: | 223 | ||
| Sequence: |
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| BDBM50344427 | |||
| n/a | |||
| Name | BDBM50344427 | ||
| Synonyms: | CHEMBL1780002 | cis-N-Benzyl-3-methoxy-N-pentyl-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H37NO2 | ||
| Mol. Mass. | 407.5882 | ||
| SMILES | CCCCCN(Cc1ccccc1)[C@H]1CC[C@]2(CC1)OC(Cc1ccccc21)OC |r,wU:13.13,16.20,(32.61,-18.88,;32.61,-20.42,;31.28,-21.19,;31.28,-22.74,;32.62,-23.5,;33.95,-22.73,;33.95,-21.19,;35.29,-20.42,;36.61,-21.19,;37.95,-20.42,;37.95,-18.88,;36.6,-18.11,;35.27,-18.88,;35.29,-23.5,;36.05,-22.15,;37.69,-22.77,;38.95,-22.36,;38.19,-23.7,;36.48,-23.08,;38.95,-20.82,;40.29,-20.05,;41.62,-20.83,;41.61,-22.36,;42.93,-23.12,;42.93,-24.64,;41.6,-25.41,;40.28,-24.64,;40.28,-23.12,;40.29,-18.51,;41.63,-17.75,)| | ||
| Structure | 
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