Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50026868 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_748646 (CHEMBL1780499) |
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Ki | 15000±n/a nM |
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Citation | Rack, E; Fröhlich, R; Schepmann, D; Wünsch, B Design, synthesis and pharmacological evaluation of spirocyclics(1) receptor ligands with exocyclic amino moiety (increased distance 1). Bioorg Med Chem19:3141-51 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50026868 |
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n/a |
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Name | BDBM50026868 |
Synonyms: | 2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-indolyl)ethyldimethylamine | 3-(2-dimethylaminoethyl)indole | 3-[2-(dimethylamino)ethyl]indole | CHEMBL12420 | DMT | N,N-dimethyl-1H-indole-3-ethylamine | N,N-dimethyltryptamine | WO2023019367, Compound DMT |
Type | Small organic molecule |
Emp. Form. | C12H16N2 |
Mol. Mass. | 188.2688 |
SMILES | CN(C)CCc1c[nH]c2ccccc12 |
Structure |
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