| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50345214 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_751966 (CHEMBL1785908) |
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| Ki | 64±n/a nM |
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| Citation |  Hen, N; Bialer, M; Yagen, B; Maresca, A; Aggarwal, M; Robbins, AH; McKenna, R; Scozzafava, A; Supuran, CT Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. J Med Chem54:3977-81 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50345214 |
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| n/a |
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| Name | BDBM50345214 |
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| Synonyms: | 2-ethyl-4-methyl-N-(4-sulfamoylphenyl)pentanamide | CHEMBL1083684 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22N2O3S |
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| Mol. Mass. | 298.401 |
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| SMILES | CCC(CC(C)C)C(=O)Nc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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