| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
|---|
| Ligand | BDBM50345222 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_751967 (CHEMBL1785909) |
|---|
| Ki | 6.5±n/a nM |
|---|
| Citation |  Hen, N; Bialer, M; Yagen, B; Maresca, A; Aggarwal, M; Robbins, AH; McKenna, R; Scozzafava, A; Supuran, CT Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. J Med Chem54:3977-81 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 14 |
|---|
| Name: | Carbonic anhydrase 14 |
|---|
| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37665.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme. |
|---|
| Residue: | 337 |
|---|
| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
|
|
|
|---|
| BDBM50345222 |
|---|
| n/a |
|---|
| Name | BDBM50345222 |
|---|
| Synonyms: | 2-ethyl-N-(4-sulfamoylphenyl)pentanamide | CHEMBL1084063 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H20N2O3S |
|---|
| Mol. Mass. | 284.374 |
|---|
| SMILES | CCCC(CC)C(=O)Nc1ccc(cc1)S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
