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TargetNeuronal acetylcholine receptor subunit alpha-7
LigandBDBM50346168
Substrate/Competitorn/a
Meas. Tech.ChEMBL_750693 (CHEMBL1785675)
Ki 733±n/a nM
Citation Breining, SR; Bencherif, M; Grady, SR; Whiteaker, P; Marks, MJ; Wageman, CR; Lester, HA; Yohannes, D Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype. Bioorg Med Chem Lett19:4359-63 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuronal acetylcholine receptor subunit alpha-7
Name:Neuronal acetylcholine receptor subunit alpha-7
Synonyms:ACHA7_MOUSE | Acra7 | Chrna7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Neuronal nicotinic acetylcholine receptor
Type:PROTEIN
Mol. Mass.:56632.61
Organism:Mus musculus
Description:ChEMBL_144033
Residue:502
Sequence:
MCGRRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL
QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHK
PRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHL
MHGTHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
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  Blast E-value cutoff:
BDBM50346168
n/a
NameBDBM50346168
Synonyms:(R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalactarate | CHEMBL1782074 | CHEMBL1783878 | CHEMBL1783879 | CHEMBL1783880 | CHEMBL1783884
TypeSmall organic molecule
Emp. Form.C6H10O8
Mol. Mass.210.1388
SMILESO[C@@H]([C@@H](O)[C@H](O)C(O)=O)[C@@H](O)C(O)=O |r|
Structure
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