| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50346381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_749997 (CHEMBL1787135) |
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| Ki | >10000±n/a nM |
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| Citation |  Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. Eur J Med Chem46:2206-16 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50346381 |
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| n/a |
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| Name | BDBM50346381 |
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| Synonyms: | CHEMBL1783352 | N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)isonicotinamidine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N6 |
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| Mol. Mass. | 398.5034 |
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| SMILES | N#CNC(=NCCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1 |w:4.4| |
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| Structure | 
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