| Reaction Details |
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 | Report a problem with these data |
| Target | Transforming protein RhoA |
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| Ligand | BDBM50347728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_756282 (CHEMBL1805095) |
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| IC50 | 1240±n/a nM |
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| Citation |  Deng, J; Feng, E; Ma, S; Zhang, Y; Liu, X; Li, H; Huang, H; Zhu, J; Zhu, W; Shen, X; Miao, L; Liu, H; Jiang, H; Li, J Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases? J Med Chem54:4508-22 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transforming protein RhoA |
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| Name: | Transforming protein RhoA |
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| Synonyms: | ARH12 | ARHA | RHO12 | RHOA | RHOA_HUMAN | Rho cDNA clone 12 | h12 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21766.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_966397 |
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| Residue: | 193 |
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| Sequence: | MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
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| BDBM50347728 |
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| n/a |
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| Name | BDBM50347728 |
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| Synonyms: | CHEMBL1802838 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N2O2 |
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| Mol. Mass. | 290.316 |
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| SMILES | OC(=O)\C=C\c1cccc(Nc2ccc3ccccc3n2)c1 |
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| Structure | 
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