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TargetArginase
LigandBDBM50350310
Substrate/Competitorn/a
Meas. Tech.ChEMBL_762138
Ki 2000000±n/a nM
Citation Ilies MDi Costanzo LDowling DPThorn KJChristianson DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase
Name:Arginase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:46502.96
Organism:Plasmodium falciparum
Description:ChEMBL_762136
Residue:411
Sequence:
MLDTIESYIKSHKEKENLYVKKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLG
WKYEDIGNIDNGDNEMKQEKKTNNYINNNDNNNDNNNDNNNDNNNNCYIPNGVIKEKKHD
LSNNKMNGYVNHNFYGNYEENNVISTNDKYKNNCYYDNIRNIKEIGIFSKNLFDTMSNEL
RKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHT
LGLFKKKVPYFEWSEKLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIY
NTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKR
VVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV
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  Blast E-value cutoff:
BDBM50350310
n/a
NameBDBM50350310
Synonyms:CHEMBL1812663
TypeSmall organic molecule
Emp. Form.C7H14BF2NO4
Mol. Mass.224.998
SMILES[NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O
Structure
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