| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM50350370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_761107 (CHEMBL1815361) |
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| Ki | 3000±n/a nM |
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| Citation |  Iwahashi, M; Shimabukuro, A; Onoda, T; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg Med Chem19:4574-88 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_MOUSE | PGE receptor, EP4 subtype | Prostanoid EP4 receptor | Ptger4 | Ptgerep4 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 56175.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 513 |
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| Sequence: | MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
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| BDBM50350370 |
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| n/a |
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| Name | BDBM50350370 |
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| Synonyms: | CHEMBL1813119 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28N2O6 |
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| Mol. Mass. | 500.5424 |
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| SMILES | COc1ccc2n(C(=O)c3ccc(OC[C@@H]4CN(C)c5ccccc5O4)cc3)c(C)c(CC(O)=O)c2c1 |r| |
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| Structure | 
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