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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM50351215 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_763895 (CHEMBL1819920) | ||
| IC50 | 14.3±n/a nM | ||
| Citation |  Brown, JR; North, EJ; Hurdle, JG; Morisseau, C; Scarborough, JS; Sun, D; Korduláková, J; Scherman, MS; Jones, V; Grzegorzewicz, A; Crew, RM; Jackson, M; McNeil, MR; Lee, RE The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem19:5585-95 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 62613.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34913 | ||
| Residue: | 555 | ||
| Sequence: |
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| BDBM50351215 | |||
| n/a | |||
| Name | BDBM50351215 | ||
| Synonyms: | CHEMBL1818415 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H24N2O2 | ||
| Mol. Mass. | 300.3954 | ||
| SMILES | COc1ccc(NC(=O)NC2C3CC4CC(C3)CC2C4)cc1 |TLB:19:18:16:12.13.14,THB:19:13:10.18.17:16,14:13:10:17.15.16,14:15:10:12.19.13,9:10:16:12.13.14,(23.71,-37.59,;25.04,-36.81,;26.38,-37.58,;27.72,-36.81,;29.05,-37.58,;29.04,-39.13,;30.38,-39.9,;31.71,-39.13,;31.71,-37.59,;33.05,-39.9,;34.38,-39.13,;35.58,-37.84,;36.91,-38.33,;38.31,-37.99,;38.33,-36.45,;36.92,-35.87,;35.57,-36.35,;35.88,-37.11,;35.88,-38.71,;37.31,-39.27,;27.72,-39.9,;26.38,-39.13,)| | ||
| Structure | 
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