Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM50351216 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_763895 (CHEMBL1819920) | ||
| IC50 | 1838.1±n/a nM | ||
| Citation |  Brown, JR; North, EJ; Hurdle, JG; Morisseau, C; Scarborough, JS; Sun, D; Korduláková, J; Scherman, MS; Jones, V; Grzegorzewicz, A; Crew, RM; Jackson, M; McNeil, MR; Lee, RE The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem19:5585-95 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 62613.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34913 | ||
| Residue: | 555 | ||
| Sequence: |
| ||
| BDBM50351216 | |||
| n/a | |||
| Name | BDBM50351216 | ||
| Synonyms: | CHEMBL1818414 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H23F3N2O | ||
| Mol. Mass. | 352.3939 | ||
| SMILES | CN(C1C2CC3CC(C2)CC1C3)C(=O)N(C)c1ccc(F)c(F)c1F |TLB:1:2:4:8.7.6,THB:2:3:6:11.10.9,2:10:4.3.8:6,9:10:4:8.7.6,9:7:4:11.2.10,(12.2,-40.47,;12.2,-38.92,;10.99,-37.96,;9.52,-38.35,;8.57,-39.58,;8.77,-37.84,;7.88,-36.65,;8.67,-35.47,;8.57,-37.08,;10.14,-35.09,;11.04,-36.34,;10.13,-37.45,;13.54,-38.15,;13.54,-36.61,;14.87,-38.92,;14.87,-40.47,;16.21,-38.15,;16.2,-36.62,;17.53,-35.84,;18.87,-36.61,;20.21,-35.84,;18.87,-38.16,;20.21,-38.93,;17.54,-38.93,;17.54,-40.47,)| | ||
| Structure | 
| ||