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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM50351239 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_763895 (CHEMBL1819920) | ||
| IC50 | 1.1±n/a nM | ||
| Citation |  Brown, JR; North, EJ; Hurdle, JG; Morisseau, C; Scarborough, JS; Sun, D; Korduláková, J; Scherman, MS; Jones, V; Grzegorzewicz, A; Crew, RM; Jackson, M; McNeil, MR; Lee, RE The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem19:5585-95 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 62613.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34913 | ||
| Residue: | 555 | ||
| Sequence: |
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| BDBM50351239 | |||
| n/a | |||
| Name | BDBM50351239 | ||
| Synonyms: | CHEMBL1818393 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H21N3O | ||
| Mol. Mass. | 295.3788 | ||
| SMILES | O=C(NC1C2CC3CC(C2)CC1C3)Nc1ccc(cc1)C#N |TLB:12:11:9:5.6.7,THB:2:3:9:5.6.7,12:6:3.11.10:9,7:6:3:10.8.9,7:8:3:5.12.6,(-.96,-25.63,;-.96,-27.17,;.38,-27.94,;1.71,-27.17,;2.9,-25.89,;4.22,-26.38,;5.62,-26.04,;5.64,-24.51,;4.23,-23.93,;2.89,-24.41,;3.19,-25.16,;3.2,-26.75,;4.61,-27.31,;-2.29,-27.94,;-3.63,-27.17,;-4.96,-27.94,;-6.3,-27.17,;-6.29,-25.63,;-4.97,-24.86,;-3.63,-25.62,;-7.64,-24.85,;-8.97,-24.09,)| | ||
| Structure | 
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