Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAutoinducer 1 sensor kinase/phosphatase luxN
LigandBDBM50351499
Substrate/Competitorn/a
Meas. Tech.ChEMBL_765226
IC50 62300±n/a nM
Citation Lowery CASalzameda NTSawada DKaufmann GFJanda KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Autoinducer 1 sensor kinase/phosphatase luxN
Name:Autoinducer 1 sensor kinase/phosphatase luxN
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:96099.26
Organism:Vibrio harveyi
Description:ChEMBL_765226
Residue:849
Sequence:
MFDFSLEAIVYAKAISLLATVAVVMMWLFYYCYRLKQKNEVIFGTHHAAYIAYSVCIIAW
ISSNAYFHTDLLPELGASAGMFMAKFANLASFFAFAFAYYFSCQLAAEQRKGKVHRWQQG
IFVSLTVYSLFINLRPGLTVEHVDIVGPSQFIIEFGPHTSYFFIGLVSFVVLTLVNLVAM
RTNSSKLTLAKTNYMIAGILVFMLSTAVIHLGMTYFMGDFSLTWLPPALSISEMLFVGYA
LLTSRFYSVKYIAYLALSVLLVCAIFVLPLGAIFIPLTESNQWLIAIPICALIGITWQLL
YKKTSRYASFLIYGDKKTPVQQILSLEEDFKLSIDDAMRRLGKLLQIPNDKLRLVTSNYN
ETFYEEYLSSNRSVLVFDELSEELEYKVSAKRSMKALYDKMSSNNTALVMPLFGQGKSVT
HLLISPHKSNNQMFSNEEISAVQTLLTRVQSTIEADRRIRQSRALANSIAHEMRNPLAQV
QLQFEALKQHIENHAPVEQITLDIENGQAAIQRGRQLIDIILREVSDSSPEHEPIAMTSI
HKAVDQAVSHYGFENEKIIERIRLPQHTDFVAKLNETLFNFVIFNLIRNAIYYFDSYPDS
QIEISTKTGPYENTLIFRDTGPGIDETISHKIFDDFFSYQKSGGSGLGLGYCQRVMRSFG
GRIECKSKLGTFTEFHLYFPVVPNAPKADTLRTPYFNDWKQNKRSNEHKVAPNVQINNQS
PTVLIVDDKEVQRALVQMYLNQLGVNSLQANNGENAVEVFKANHVDLILMDVQMPVMNGF
DASQRIKELSPQTPIVALSGESGERELDMINKLMDGRLEKPTTLNALRHVLGNWLNKNTA
SSACEAERE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50351499
n/a
NameBDBM50351499
Synonyms:CHEMBL1823950
TypeSmall organic molecule
Emp. Form.C12H14N2O2S
Mol. Mass.250.317
SMILESCC(C)OC(=O)CSc1nc2ccccc2[nH]1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: