| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Autoinducer 1 sensor kinase/phosphatase LuxN |
|---|
| Ligand | BDBM50351499 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_765226 (CHEMBL1827779) |
|---|
| IC50 | 62300±n/a nM |
|---|
| Citation |  Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem53:7467-89 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Autoinducer 1 sensor kinase/phosphatase LuxN |
|---|
| Name: | Autoinducer 1 sensor kinase/phosphatase LuxN |
|---|
| Synonyms: | LUXN_VIBHA | luxN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 96099.26 |
|---|
| Organism: | Vibrio harveyi |
|---|
| Description: | ChEMBL_765226 |
|---|
| Residue: | 849 |
|---|
| Sequence: | MFDFSLEAIVYAKAISLLATVAVVMMWLFYYCYRLKQKNEVIFGTHHAAYIAYSVCIIAW
ISSNAYFHTDLLPELGASAGMFMAKFANLASFFAFAFAYYFSCQLAAEQRKGKVHRWQQG
IFVSLTVYSLFINLRPGLTVEHVDIVGPSQFIIEFGPHTSYFFIGLVSFVVLTLVNLVAM
RTNSSKLTLAKTNYMIAGILVFMLSTAVIHLGMTYFMGDFSLTWLPPALSISEMLFVGYA
LLTSRFYSVKYIAYLALSVLLVCAIFVLPLGAIFIPLTESNQWLIAIPICALIGITWQLL
YKKTSRYASFLIYGDKKTPVQQILSLEEDFKLSIDDAMRRLGKLLQIPNDKLRLVTSNYN
ETFYEEYLSSNRSVLVFDELSEELEYKVSAKRSMKALYDKMSSNNTALVMPLFGQGKSVT
HLLISPHKSNNQMFSNEEISAVQTLLTRVQSTIEADRRIRQSRALANSIAHEMRNPLAQV
QLQFEALKQHIENHAPVEQITLDIENGQAAIQRGRQLIDIILREVSDSSPEHEPIAMTSI
HKAVDQAVSHYGFENEKIIERIRLPQHTDFVAKLNETLFNFVIFNLIRNAIYYFDSYPDS
QIEISTKTGPYENTLIFRDTGPGIDETISHKIFDDFFSYQKSGGSGLGLGYCQRVMRSFG
GRIECKSKLGTFTEFHLYFPVVPNAPKADTLRTPYFNDWKQNKRSNEHKVAPNVQINNQS
PTVLIVDDKEVQRALVQMYLNQLGVNSLQANNGENAVEVFKANHVDLILMDVQMPVMNGF
DASQRIKELSPQTPIVALSGESGERELDMINKLMDGRLEKPTTLNALRHVLGNWLNKNTA
SSACEAERE
|
|
|
|---|
| BDBM50351499 |
|---|
| n/a |
|---|
| Name | BDBM50351499 |
|---|
| Synonyms: | CHEMBL1823950 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H14N2O2S |
|---|
| Mol. Mass. | 250.317 |
|---|
| SMILES | CC(C)OC(=O)CSc1nc2ccccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
