| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50046952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_765939 (CHEMBL1827955) |
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| Ki | 22±n/a nM |
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| Citation |  Wang, W; Cui, J; Lu, X; Padakanti, PK; Xu, J; Parsons, SM; Luedtke, RR; Rath, NP; Tu, Z Synthesis and in vitro biological evaluation of carbonyl group-containing analogues fors1 receptors. J Med Chem54:5362-72 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50046952 |
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| n/a |
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| Name | BDBM50046952 |
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| Synonyms: | (3'R,4'R)-1'-(4-Fluoro-benzyl)-4-phenyl-[1,3']bipiperidinyl-4'-ol | CHEMBL129530 | CHEMBL1956464 | p-fluorobenzyltrozamicol | trans-1-(4-fluorobenzyl)-3-(4-phenylpiperidin-1-yl)piperidin-4-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29FN2O |
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| Mol. Mass. | 368.4876 |
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| SMILES | O[C@@H]1CCN(Cc2ccc(F)cc2)C[C@H]1N1CCC(CC1)c1ccccc1 |r| |
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| Structure | 
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