Reaction Details |
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Target | Melatonin receptor type 1B |
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Ligand | BDBM50352003 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_766804 (CHEMBL1827744) |
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Ki | 0.2±n/a nM |
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Citation | El Kazzouli, S; Griffon du Bellay, A; Berteina-Raboin, S; Delagrange, P; Caignard, DH; Guillaumet, G Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands. Eur J Med Chem46:4252-7 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Melatonin receptor type 1B |
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Name: | Melatonin receptor type 1B |
Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
Type: | Enzyme |
Mol. Mass.: | 40203.54 |
Organism: | Homo sapiens (Human) |
Description: | P49286 |
Residue: | 362 |
Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50352003 |
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n/a |
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Name | BDBM50352003 |
Synonyms: | CHEMBL1823015 |
Type | Small organic molecule |
Emp. Form. | C18H19N3O2 |
Mol. Mass. | 309.3624 |
SMILES | COc1ccc2[nH]c(c(CCNC(C)=O)c2n1)-c1ccccc1 |
Structure |
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