| Reaction Details |
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 | Report a problem with these data |
| Target | 3-dehydroquinate dehydratase |
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| Ligand | BDBM50352023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_766424 (CHEMBL1826564) |
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| Ki | 14600±n/a nM |
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| Citation |  Tizón, L; Otero, JM; Prazeres, VF; Llamas-Saiz, AL; Fox, GC; van Raaij, MJ; Lamb, H; Hawkins, AR; Ainsa, JA; Castedo, L; González-Bello, C A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors. J Med Chem54:6063-84 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-dehydroquinate dehydratase |
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| Name: | 3-dehydroquinate dehydratase |
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| Synonyms: | AROQ_HELPY | aroQ |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18479.08 |
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| Organism: | Helicobacter pylori |
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| Description: | ChEMBL_766424 |
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| Residue: | 167 |
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| Sequence: | MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIID
KIQESVGSDYEGIIINPGAFSHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGA
ACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNNPNNPINNQK
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| BDBM50352023 |
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| n/a |
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| Name | BDBM50352023 |
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| Synonyms: | CHEMBL1823567 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17O6S2 |
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| Mol. Mass. | 381.444 |
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| SMILES | O[C@@H]1C[C@](O)(C([O-])=O)C(Cc2cccs2)=C(OCc2cccs2)[C@H]1O |r,t:15| |
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| Structure | 
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