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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H3 receptor | ||
| Ligand | BDBM50352094 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766550 (CHEMBL1827031) | ||
| Ki | 0.56±n/a nM | ||
| Citation |  Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series. Bioorg Med Chem Lett21:5384-8 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H3 receptor | |||
| Name: | Histamine H3 receptor | ||
| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 48691.47 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50352094 | |||
| n/a | |||
| Name | BDBM50352094 | ||
| Synonyms: | CHEMBL1824237 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H42N2O | ||
| Mol. Mass. | 398.6245 | ||
| SMILES | CC1CCN(CC1)[C@H]1CC[C@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 |r,wU:10.14,7.7,(24.57,-13.55,;23.03,-13.53,;22.24,-14.85,;20.71,-14.83,;19.96,-13.49,;20.73,-12.16,;22.28,-12.18,;18.42,-13.48,;17.64,-14.8,;16.1,-14.79,;15.34,-13.45,;16.11,-12.12,;17.66,-12.14,;13.8,-13.44,;13.02,-14.76,;11.49,-14.76,;10.72,-13.42,;9.19,-13.41,;8.41,-14.75,;6.87,-14.74,;6.11,-13.41,;4.57,-13.41,;3.8,-14.73,;2.26,-14.73,;1.49,-13.41,;2.26,-12.07,;3.8,-12.07,;11.49,-12.09,;13.03,-12.1,)| | ||
| Structure | 
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