| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M4 |
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| Ligand | BDBM50352153 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_767226 (CHEMBL1826472) |
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| Ki | 1784±n/a nM |
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| Citation |  Banister, SD; Yoo, DT; Chua, SW; Cui, J; Mach, RH; Kassiou, M N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (s) receptor ligands. Bioorg Med Chem Lett21:5289-92 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M4 |
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| Name: | Muscarinic acetylcholine receptor M4 |
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| Synonyms: | ACM4_HUMAN | CHRM4 | Cholinergic, muscarinic M4 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M2 and M4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 53079.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Cholinergic, muscarinic M4 CHRM4 HUMAN M3::P08173 |
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| Residue: | 479 |
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| Sequence: | MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
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| BDBM50352153 |
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| n/a |
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| Name | BDBM50352153 |
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| Synonyms: | CHEMBL1824784 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N |
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| Mol. Mass. | 227.3446 |
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| SMILES | C(N1C2CC3CC(C2)CC1C3)c1ccccc1 |TLB:10:9:7:3.4.5,THB:10:4:1.9.8:7,5:4:1:8.6.7,5:6:1:3.10.4,0:1:7:3.4.5| |
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| Structure | 
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