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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Somatostatin receptor type 3 | ||
| Ligand | BDBM50136824 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766830 (CHEMBL1827863) | ||
| IC50 | 13±n/a nM | ||
| Citation |  Erchegyi, J; Cescato, R; Waser, B; Rivier, JE; Reubi, JC N-imidazolebenzyl-histidine substitution in somatostatin and in its octapeptide analogue modulates receptor selectivity and function. J Med Chem54:5981-7 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Somatostatin receptor type 3 | |||
| Name: | Somatostatin receptor type 3 | ||
| Synonyms: | SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3) | ||
| Type: | Protein | ||
| Mol. Mass.: | 45855.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P32745 | ||
| Residue: | 418 | ||
| Sequence: |
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| BDBM50136824 | |||
| n/a | |||
| Name | BDBM50136824 | ||
| Synonyms: | (4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl)methyl)-25-amino-13-(4-aminobutyl)-7,19,22-tribenzyl-10-((R)-1-hydroxyethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosane-4-carboxylic acid | (S)-25-Amino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,12,15,18-tetra(S)-oxo-9,21-di(R)-oxo-24-oxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid | CHEMBL266477 | H-c(Cys3-Phe6-Phe7-DTrp8-Lys9-Thr10-Phe11-Cys14)-OH | ODT-8 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C54H66N10O10S2 | ||
| Mol. Mass. | 1079.293 | ||
| SMILES | C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O | ||
| Structure | 
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