| Reaction Details |
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 | Report a problem with these data |
| Target | Branched-chain-amino-acid aminotransferase, cytosolic |
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| Ligand | BDBM50353005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_767755 (CHEMBL1825867) |
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| IC50 | 230±n/a nM |
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| Citation |  Mendoza, R; Petros, AM; Liu, Y; Thimmapaya, R; Surowy, CS; Leise, WF; Pereda-Lopez, A; Panchal, SC; Sun, C Cracking the molecular weight barrier: fragment screening of an aminotransferase using an NMR-based functional assay. Bioorg Med Chem Lett21:5248-50 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Branched-chain-amino-acid aminotransferase, cytosolic |
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| Name: | Branched-chain-amino-acid aminotransferase, cytosolic |
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| Synonyms: | BCAT1 | BCAT1_HUMAN | BCT1 | Branched-chain-amino-acid transferase | ECA39 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42957.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1516919 |
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| Residue: | 386 |
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| Sequence: | MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV
EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM
YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK
ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN
GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ
WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK
LASRILSKLTDIQYGREESDWTIVLS
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| BDBM50353005 |
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| n/a |
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| Name | BDBM50353005 |
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| Synonyms: | CHEMBL1231666 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10ClF3N2O4S |
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| Mol. Mass. | 418.775 |
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| SMILES | FC(F)(F)c1ccccc1S(=O)(=O)NNC(=O)c1cc2cc(Cl)ccc2o1 |
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| Structure | 
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