| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 1 |
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| Ligand | BDBM50353441 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_769117 (CHEMBL1832674) |
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| Ki | >25000±n/a nM |
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| Citation |  Page, BD; Fletcher, S; Yue, P; Li, Z; Zhang, X; Sharmeen, S; Datti, A; Wrana, JL; Trudel, S; Schimmer, AD; Turkson, J; Gunning, PT Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain. Bioorg Med Chem Lett21:5605-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 1 |
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| Name: | Signal transducer and activator of transcription 1 |
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| Synonyms: | STAT1_MOUSE | Stat1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 87184.30 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_863014 |
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| Residue: | 749 |
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| Sequence: | MSQWFELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIYNCLKEERKILENAQ
RFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEQEIKTLEELQDEYDFKCKTSQNR
EGEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWK
RRQQSACIGGPPNACLDQLQTWFTIVAETLQQIRQQLKKLEELEQKFTYEPDPITKNKQV
LSDRTFLLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKSRLLVKLQESNLLTKV
KCHFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAELRHLQLKEQKNAGNRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVTE
PRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPDGLIPWT
RFCKENINDKNFSFWPWIDTILELIKNDLLCLWNDGCIMGFISKERERALLKDQQPGTFL
LRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP
ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEVHPSRLQTT
DNLLPMSPEEFDEMSRIVGPEFDSMMSTV
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| BDBM50353441 |
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| n/a |
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| Name | BDBM50353441 |
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| Synonyms: | CHEMBL1829786 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H34N2O6S |
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| Mol. Mass. | 550.666 |
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| SMILES | CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1ccc(C)cc1 |
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| Structure | 
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