| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 7 |
|---|
| Ligand | BDBM50354085 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_770953 (CHEMBL1838192) |
|---|
| IC50 | 24000±n/a nM |
|---|
| Citation |  Wang, C; Henkes, LM; Doughty, LB; He, M; Wang, D; Meyer-Almes, FJ; Cheng, YQ Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities. J Nat Prod74:2031-8 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 7 |
|---|
| Name: | Histone deacetylase 7 |
|---|
| Synonyms: | HD7 | HDAC7 | HDAC7A | HDAC7_HUMAN | Histone acetylase 7 (HDAC7) | Histone deacetylase 7A | Human HDAC7 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 102942.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8WUI4 |
|---|
| Residue: | 952 |
|---|
| Sequence: | MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVG
PQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPL
ETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKE
SAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSV
APFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGG
TLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEP
LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVV
DDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRP
LSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSR
HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG
FAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQ
DPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRI
VVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQR
LASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
|
|
|
|---|
| BDBM50354085 |
|---|
| n/a |
|---|
| Name | BDBM50354085 |
|---|
| Synonyms: | CHEMBL1836042 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H41N3O6S2 |
|---|
| Mol. Mass. | 531.729 |
|---|
| SMILES | CCCC[C@H]1NC(=O)C[C@H](OC(=O)C[C@H](O)[C@H](NC(=O)[C@@H](CS)NC1=O)[C@@H](C)CC)\C=C\CCS |r| |
|---|
| Structure | 
|
|---|
Search and Browse
